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Showing posts with label SyntheticBiology. Show all posts
Showing posts with label SyntheticBiology. Show all posts

Wednesday, May 1, 2024

Ginkgo Bioworks is building out their BioManufacturing Foundry platform which mimics the building of semiconductor foundries of yester year!

 78.63% of #GinkgoBioworks ( $DNA) stock is owned by #Institutional #investors.

Here are some of the major institutional shareholders:

ARK Investment Management LLC owns a significant number of shares in Ginkgo Bioworks Holdings, Inc. (NYSE: DNA). As of the most recent filings, they held 182,192,185 shares during the 3rd quarter of 2023. 
Equitec Proprietary Markets LLC: Holds 672,488 shares (0.5% of the portfolio). Sumitomo Mitsui Trust Holdings Inc.: Holds 55,865,048 shares (2.595% of the portfolio).
(Note: M. Potter who served as President, Chief Executive Officer, and Chair of the board of Sumitomo Pharma America, and as the Chief Executive Officer of Sumitovant Biopharma, the parent company of five biotechnology companies, was added to the board of Ginkgo BioWorks on April 29th) Salem Investment Counselors Inc.: Holds 4,758,585 shares (0.221% of the portfolio). Vanguard Group Inc.: Holds 132,780,095 shares (6.169% of the portfolio). Lingotto Investment Management LLP: Holds 8,511,301 shares (0.402% of the portfolio). Additionally, during the previous two years, a total of 228 institutional investors and hedge funds held shares of Ginkgo Bioworks.
Some of the most heavily invested institutions include Baillie Gifford & Co., ARK Investment Management LLC, and Nikko Asset Management Americas Inc.. Institutional investors play a significant role in Ginkgo Bioworks’ ownership structure, with a mix of large investment firms and hedge funds holding substantial stakes in the company

Founded in 2008 by five #Scientists from #MIT, Ginkgo Bioworks is headquartered in #Boston. Their mission is to use #Biology to grow better products across diverse markets. They have developed a cell programming platform that enables the growth of biotechnology. Ginkgo’s platform allows for programming cells and designing organisms that behave in pre-defined ways. They work with various industries, from food to fragrance to pharmaceuticals. - - - - - - -
#Ginkgo collaborates with various organizations and companies like:
Pfizer
Pfizer has entered into a multi-target RNA discovery collaboration with Ginkgo Bioworks, cell engineering.
Ginkgo also collaborates with these partners:

#Motif #FoodWorks: Changing the future of #food. #Bayer: Designing #probiotics for plants. #Allonnia: Enabling bioremediation solutions. #Aldevron: Supporting the #Vaccine #SupplyChain. #Cronos Group: Unlocking potential in #Cannabinoids. #Synlogic: Engineering living #Medicines. #Moderna: Optimizing vaccine processes. #IARPA: Protecting valuable technology. #Robertet: Producing cultured ingredients. And more

  • Keep in mind the companies that collaborate with Ginkgo Bioworks to advance synthetic biology:

    1. OneOne Biosciences

      , a French biotech startup, is developing a comprehensive suite of agricultural microbial solutions. They have partnered with Ginkgo Bioworks to leverage their robust ag biologicals infrastructure, biotechnological expertise, and Strain Optimization Services. The collaboration aims to accelerate OneOne’s research and product development in agricultural microbial solutions, including a novel solution for production and delivery of ag microbials through the OneOne Multiplier™1.
    2. Synlogic: collaborates with Ginkgo Bioworks to develop a pipeline of novel “living” medicines based on engineered probiotics. They utilize Ginkgo’s cell programming platform to create innovative treatments.

    3. Biogen:

       and Ginkgo Bioworks have announced a gene therapy collaboration. Their goal is to redefine the industry standard for manufacturing recombinant adeno-associated virus (AAV)-based vectors3.

    4. Pfizer: Ginkgo Bioworks has a collaboration with Pfizer to advance the discovery and development of novel RNA molecules across priority research areas using Ginkgo’s proprietary RNA technology4.


    Ginkgo has also acquired competitors like Zymergen etc, and have a serious "first mover" advantage in the field as they continue to build a "moat" around their business that few if any, will be able to copykey points:
    1. Sustainability: Ginkgo’s platform enables leading pharmaceutical, food, and agriculture companies to develop more sustainable solutions. As the world increasingly looks to synthetic biology for emissions reduction and supply chain resilience, Ginkgo’s role becomes more critical.

    2. Biosecurity:

      Ginkgo’s biosecurity business unit, Concentric, is working on building infrastructure to monitor biological threats. They collaborate with organizations like the Centers for Disease Control and Prevention (CDC) to enhance pathogen monitoring and develop tools to prevent misuse of engineered biology.

    3. Employee Ownership and Care: Ginkgo is committed to thoughtful deployment of its platform. They’ve established a Caring Committee to assess potential impacts of their activities and integrate a Cost, Caring, and Risk Assessment (CCRA) process

    4. How to invest in Robots and Robotics going forward, through the back door method!