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Showing posts with label Recursion Pharmaceuticals. Show all posts
Showing posts with label Recursion Pharmaceuticals. Show all posts

Wednesday, July 23, 2025

Why do Nvidia and so many institutional investors own most of the shares of RXRX - Recursion Pharma

 


Why Nvidia Invested in RXRX

1. Deep AI Integration for Drug Discovery

  • In July 2023, Nvidia invested $50 million via a PIPE deal to help Recursion accelerate training of AI models for drug discovery. This investment boosted RXRX stock by about 83% immediately Reuters

  • Nvidia provided cutting-edge GPUs and access to its BioNeMo generative-AI cloud platform so Recursion could train models on its massive biological dataset MarketWatch+2.

2. Equity Stake & Strategic Synergy

  • Nvidia now holds over 7.7 million shares—approximately a 3–4% stake—making Recursion one of its top non-core holdings The Times+11

  • This aligns with Nvidia’s broader strategy of investing in AI-first companies that complement its hardware, not just selling chips.

3. Accelrating RXRX’s Supercomputer Ambitions

  • Recursion built BioHive‑2, a supercomputer powered by Nvidia’s DGX H100 GPUs. It delivers a 4x speed increase over their prior system, enabling faster model training Reuters+2T

  • This partnership helps validate Nvidia hardware in high-performance biotech applications—which can drive future sales to pharma partners.


๐Ÿฅ Broader Vision: Redefining Pharma with AI

  • Recursion uses AI, automation, and robotics to develop drugs more quickly and affordably. Its platform includes the “virtual cell” paradigm and is backed by major pharma companies like Bayer and Roche Investors+14.

  • Analysts project RXRX revenue growing at a ~65–73% CAGR through 2027—significantly above typical biotech growth—with Nvidia’s backing lending extra credibility The Motley Fool+5

✅ Summary

Nvidia's investment in RXRX is twofold:

  1. Financial Buy-In – it gains exposure to a high-growth biotech using AI and fosters long-term capital appreciation.

  2. Strategic Alignment – Nvidia deepens integration of its AI stack (hardware + BioNeMo) in the drug discovery workflow, while demonstrating its systems’ performance in real-world pharma applications.

It’s part of a broader strategy of deploying capital into AI-first companies that can both benefit from and validate Nvidia’s ecosystem, accelerating adoption across industries.


Here are the top ten institutional investors in Recursion Pharmaceuticals (RXRX), based on the most recently reported 13F filings (as of March 31, 2025) and aggregated data sources Yahoo Finance+12:


๐Ÿฆ Top 10 Institutional Holders of RXRX

Ranked by percentage ownership:

  1. ARK Investment Management LLC — 8.66% (~34.8M shares; ~$184 M) 

  2. Vanguard Group Inc. — 8.03% (~32.3M shares; ~$171 M) 

  3. Lux Ventures IV LP — 7.46% (~30.3M shares; ~$194 M) 

    1. Baillie Gifford & Co. — 6.07% (~24.4M shares; ~$129 M)
  4. BlackRock Inc. — 5.78% (~23.5M shares; ~$150 M) 

  5. SoftBank Group Corp. — 3.61% (~14.7M shares; ~$94 M) 

  6. Kinnevik AB (publ) — 3.30% (~13.4M shares; ~$86 M) 

  7. State Street Corp. — 3.22% (~13.1M shares; ~$84 M) 

  8. Mubadala Investment Co. PJSC — 3.19% (~13.0M shares; ~$83 M) 

  9. Novo Holdings A/S — 2.38% (~9.7M shares; ~$62 M) 

๐Ÿงพ Summary Table

Investor% OwnershipApprox. Shares
ARK Investment Management LLC8.66%~34.8 M
Vanguard Group Inc.8.03%~32.3 M
Lux Ventures IV LP7.46%~30.3 M
Baillie Gifford & Co.6.07%~24.4 M
BlackRock Inc.5.78%~23.5 M
SoftBank Group Corp.3.61%~14.7 M
Kinnevik AB (publ)3.30%~13.4 M
State Street Corp.3.22%~13.1 M
Mubadala Investment Co. PJSC3.19%~13.0 M
Novo Holdings A/S2.38%~9.7 M

๐Ÿ’ก Key Insights

  • Institutional investors control around 75% of RXRX's outstanding shares Nasdaq+

  • ARK and Vanguard are the two largest, with each holding over 8% of the company.

  • Lux Ventures IV LP—a prominent insider-linked investor—is effectively the third-largest stakeholder at ~7.5%.

  • Other heavyweights include Baillie Gifford, BlackRock, SoftBank, and sovereign/strategic holders like Mubadala and Novo Holdings.


Here’s a breakdown of the recent moves by institutional investors in RXRX:


๐Ÿ“ˆ Increased Positions (Recent Quarter)

  • UBS Asset Management Americas (UBS AM) added 4.15M shares (+183.7%) in Q1 2025 (~$22M) MarketBeat+

  • UBS Group AG boosted its stake by 2.57M shares (+85.4%) (~$13.6M) 

  • According to CapEdge filings (as of July 22, 2025):

    • KLP Kapitalforvaltning AS increased by +20% (~61K shares)

    • Steel Peak Wealth Management up +21% (~85K shares)

    • Prime Capital Investment Advisors boosted by +61% (~30K shares)

    • IMC‑Chicago surged +76% (~284K shares) 

๐Ÿ“‰ Reduced or Exited Positions

  • RA Capital Management, L.P. fully exited its position, selling 7.73M shares (~$41M) in Q1 2025 

  • CapEdge data shows QRG Capital Management reduced its holding by 32% (~19K shares) as of July 21, 2025 

๐Ÿ” Additional Context

  • Total institutional inflows over the past 24 months reached significantly more than outflows:

    • 83.2M shares purchased (~$550M)

    • 18.3M shares sold (~$117M) MarketBeat

    • This reflects overall upward interest, but pockets of profit-taking and rotation remain.

  • Other Q1 fourth-quarter buyers included firms like Brighton Jones, Victory Capital, and Private Advisor Group, while sellers included RA Capital prominently MarketBeatMarketBeat.


✅ Summary

  • UBS (both global and Americas units) made the largest scale-ups recently.

  • RA Capital initiated the most substantial reduction, liquidating its entire stake.

  • Mid-cap managers like KLP, Steel Peak, Prime Capital, and IMC‑Chicago also significantly expanded their RXRX positions.

  • Some smaller managers, including QRG Capital, reduced or trimmed their positions.


  • ED Note:  We are long RXRX

Tuesday, March 11, 2025

Nvidia's interest and investment in Recursion Pharmaceuticals (RXRX) in 2025 could be a game changer for this small-cap!

 

 


Recursion Pharmaceuticals (NASDAQ: RXRX) is a clinical-stage biotechnology company that integrates advanced technologies across biology, chemistry, automation, data science, and engineering to decode complex biological systems. Here's an updated overview of the company's financials, partnerships, technological advancements, product pipeline, and other pertinent information:

Financial Overview

  • Cash Position: As of December 31, 2024, Recursion reported cash, cash equivalents, and restricted cash totaling $603.0 million, up from $401.4 million on the same date in 2023.ir.recursion.com

  • Revenue: The company achieved total revenue of $83 million for the fiscal year 2024, reflecting a strong financial performance.tipranks.com

  • Research and Development Expenses: R&D expenses were $74.6 million for Q3 2024, up from $70.0 million in Q3 2023, indicating continued investment in platform expansion and upgrades.globenewswire.com

  • Net Loss: The net loss for Q3 2024 was $95.8 million, compared to $93.0 million in Q3 2023, reflecting ongoing investments in research and development.globenewswire.com

Strategic Partnerships

  • NVIDIA: In July 2023, NVIDIA invested $50 million in Recursion to accelerate the development of AI foundation models for biology and chemistry. This collaboration leverages Recursion's extensive proprietary dataset and NVIDIA's cloud services, including the DGX™ Cloud and BioNeMo platform, to enhance drug discovery capabilities.en.wikipedia.org

  • Roche and Genentech: In December 2021, Recursion entered into a partnership with Roche and its subsidiary Genentech, potentially worth up to $12 billion, to advance therapies in neuroscience and other areas.en.wikipedia.org

  • Bayer: The company has a strategic collaboration with Bayer focusing on oncology research, building upon a previous partnership targeting fibrotic diseases.en.wikipedia.org

  • Exscientia Acquisition: In August 2024, Recursion acquired UK-based biotechnology company Exscientia for $688 million, adding a technology-enabled clinical pipeline and precision chemistry capabilities.globenewswire.com+1en.wikipedia.org+1

Technological Infrastructure

  • Recursion OS: The company's proprietary operating system integrates wet-lab and dry-lab biology experiments, enabling the generation of massive datasets to map and navigate complex biological relationships.sec.gov

  • BioHive-2 Supercomputer: In May 2024, Recursion completed BioHive-2, an NVIDIA-powered AI supercomputer comprising 63 DGX H100 systems with a total of 504 NVIDIA H100 Tensor Core GPUs. Ranked #35 in the TOP500 list of the world's most powerful supercomputers, BioHive-2 significantly enhances Recursion's computational capabilities, facilitating more efficient training of large-scale AI models.

Product Pipeline and Clinical Developments

  • REC-994: This experimental drug targets cerebral cavernous malformation (CCM), a rare brain-related condition. In a mid-stage study reported in September 2024, REC-994 demonstrated safety and tolerability. MRI-based data indicated that the highest dose reduced the number of lesions. However, improvements reported by patients or doctors were not observed at the end of the 12-month treatment period. Recursion plans to meet with the U.S. Food and Drug Administration to discuss further clinical studies.Reuters

  • Clinical Trial Outlook: Recursion anticipates seven clinical trial readouts over the next 18 months for its programs and approximately ten readouts collectively over the same period, including those from the Exscientia acquisition.globenewswire.com+1en.wikipedia.org+1

Intellectual Property

  • Patent Portfolio: As of February 2025, Recursion holds a total of 149 patents globally, with 58 granted. Notably, over 78% of these patents remain active. The majority are filed in the United States, followed by Europe and Canada.

Conclusion

Recursion Pharmaceuticals continues to leverage its robust financial position, strategic partnerships, and advanced technological infrastructure to pioneer AI-driven drug discovery and development. The company's expanding patent portfolio and active clinical pipeline underscore its commitment to transforming the pharmaceutical industry through innovative approaches to complex diseases.

Nvidia-backed Recursion's shares fall on mixed data for rare disorder drug
FaviconReuters

Thursday, February 20, 2025

In 2025, the biotechnology sector is witnessing transformative advancements, with several companies at the forefront of revolutionizing medicine

 


Here is a very brief overview of why we are investing in these cutting edge BioTech Stocks now!

Below is a comparative overview of Intellia Therapeutics, Editas Medicine, Beam Therapeutics, Recursion Pharmaceuticals, Viking Therapeutics, Royalty Pharma, and Ginkgo Bioworks, highlighting their unique contributions and potential impact on healthcare.

1. Intellia Therapeutics (NASDAQ: NTLA)

Intellia Therapeutics is a clinical-stage gene-editing company leveraging CRISPR/Cas9 technology to develop in vivo therapies. Their pipeline includes treatments for genetic diseases such as transthyretin amyloidosis (ATTR) and hereditary angioedema. Intellia's approach involves precise editing of disease-causing genes directly within the human body, aiming to provide curative solutions.

2. Editas Medicine (NASDAQ: EDIT)

Editas Medicine focuses on developing genome-editing technologies to treat a range of serious diseases by targeting their genetic causes. Their lead program, EDIT-101, is designed to treat Leber Congenital Amaurosis 10 (LCA10), a genetic eye disorder, by delivering gene-editing components directly to retinal cells. This approach aims to restore vision in affected individuals.

3. Beam Therapeutics (NASDAQ: BEAM)

Beam Therapeutics specializes in precision genetic medicines through base editing, a next-generation CRISPR technology that enables precise edits at the single-base level without causing double-stranded DNA breaks. This method holds promise for treating various genetic disorders with enhanced safety and efficacy.

4. Recursion Pharmaceuticals (NASDAQ: RXRX)

Recursion Pharmaceuticals integrates artificial intelligence (AI) with experimental biology to discover novel therapeutic candidates. By automating high-throughput experiments and applying machine learning algorithms, Recursion aims to accelerate drug discovery and repurpose existing drugs for new indications, potentially transforming the pharmaceutical development landscape.

5. Viking Therapeutics (NASDAQ: VKTX)

Viking Therapeutics is a clinical-stage biopharmaceutical company focused on developing novel therapies for metabolic and endocrine disorders. Their lead candidates target conditions such as non-alcoholic steatohepatitis (NASH) and dyslipidemia, aiming to address significant unmet medical needs in liver and lipid disorders.

6. Royalty Pharma (NASDAQ: RPRX)

Royalty Pharma acquires pharmaceutical royalties and funds innovation across the biopharmaceutical industry. By providing capital to research and development efforts, Royalty Pharma plays a crucial role in bringing new therapies to market, thereby indirectly influencing the advancement of medical treatments.

7. Ginkgo Bioworks (NYSE: DNA)

Ginkgo Bioworks specializes in synthetic biology, utilizing advanced genetic engineering to design custom organisms for various applications, including pharmaceuticals. Their platform enables the development of novel therapeutics and the optimization of existing biological processes, potentially leading to more efficient and cost-effective drug production.

In summary, these companies exemplify the diverse strategies employed to advance medical science. From gene editing and AI-driven drug discovery to synthetic biology and strategic investments, each plays a unique role in shaping the future of healthcare, offering hope for more effective and personalized treatments.

Tuesday, September 17, 2024

Investing in Recursion Pharmaceuticals Inc. (NASDAQ: RXRX) at the intersection of biotechnology and advanced computational methods.

 


Here are several reasons why someone might consider investing in the company:

  1. Innovative Drug Discovery Platform: Recursion leverages artificial intelligence (AI), machine learning, and high-throughput experimentation to accelerate drug discovery and development. Their platform aims to transform traditional methods by rapidly identifying potential therapeutics across a broad range of diseases.

  2. Robust and Diverse Pipeline: The company has a pipeline that includes candidates for rare genetic diseases, oncology, and inflammation. A successful approval and commercialization of any of these candidates could lead to significant revenue growth.

  3. Strategic Partnerships: Recursion has established collaborations with major pharmaceutical companies like Bayer and Roche. These partnerships not only provide financial support but also validate the company's technology and approach.

  4. Market Potential: By targeting diseases with high unmet medical needs, Recursion positions itself in markets with substantial growth opportunities. Success in these areas could lead to significant market share and profitability.

  5. Experienced Leadership: The management team comprises experts in biotechnology, computational biology, and data science. Their combined expertise enhances the company's ability to navigate the complex landscape of drug development.

  6. Cutting-Edge Technology: The integration of AI and machine learning in drug discovery is a growing trend. As an early adopter, Recursion could capitalize on advancements in computational biology, giving it a competitive edge.

  7. Financial Health: The company has secured substantial funding through public offerings and private investments, providing a solid financial runway to advance its research and development efforts.

  8. Intellectual Property Portfolio: A strong portfolio of patents and proprietary technologies can protect the company's competitive position and provide potential licensing opportunities.

  9. Potential for High Returns: Early-stage biotech companies often offer the possibility of significant returns, especially if their drug candidates successfully reach the market.

  10. Positive Industry Outlook: The biotech sector continues to grow, driven by advancements in technology and an increasing demand for innovative therapeutics.

Considerations and Risks:

  • Regulatory Hurdles: Drug development involves rigorous clinical trials and regulatory approvals, which are time-consuming and expensive with no guarantee of success.
  • Market Competition: The biotech field is highly competitive, with many companies vying to develop similar therapies.
  • Financial Risk: Biotechnology companies often operate at a loss during their development stages and may require additional funding.
  • Technological Challenges: Relying heavily on AI and machine learning introduces risks related to technological failures or limitations.

Disclaimer: Investing in biotechnology stocks involves significant risks, including the potential loss of your entire investment. This information is for educational purposes only and should not be considered financial advice. It is important to conduct your own research and consult with a qualified financial advisor before making any investment decisions.

Here are ten small-cap, publicly traded companies that are incorporating cutting-edge AI technology into healthcare!